This paper argues changing pattern of combination on zones and layers of inland markets and their relationships with open ports in lower Yangzi River Delta after 1860's with Chinkinang (Zhenjiang) port as a focus. Chinkinag (Zhenjiang) located at the crossroad of the Yangzi River and the Grand Canal and covered the largest numbers of inland markets ranging from Shandong, Jiangsu, Hunan to Hubei provinces. Chinkinag Maritime Custom issued transit passes to foreign merchants to exempt holders further inland taxes such as Likin and reported detailed trade statistics with destination, amount and price of the 17 foreign and domestic commodities such as cotton textile and sugar sold to more than 300 markets from 1868 to 1881. These statistics make us possible to figure out different inland market zones through changing circulation of commodities and their relationships with open ports. Thus, we will re-examine port-hinterland model and the theory of marketing structure.